General
This subject covers the basic concepts of microbial growth kinetic and stoichiometry in different bioreactor operational modes. This subject also emphasizes on the design feature, sterilization, and scale-up of a bioreactor.
Bioreactor Engineering
Topic outline
Chapter 1: Introduction of Bioprocess Engineering
- Introduction to Bioprocess Engineering
- Introduction to Fermentation
Please do the assignment.
Chapter 2: Culture Kinetic Study of Batch Fermentation
- Kinetics of Cell Growth and Death
- Kinetics of Substrate Consumption
- Kinetics of Product Formation
Please do the exercise.
Chapter 3: Culture Kinetic Study of Continuous Fermentation
- Kinetics of Cell Growth
- Kinetics of Substrate Consumption
- Kinetics of Product Formation
Please do the exercise.
Chapter 4: Operation Considerations For Bioreactor
- Choosing Cultivation Method
Please do the exercise.
Chapter 5: Culture Kinetic Study of Modifying Batch Fermentation
- Feb-batch Operation
Please do the exercise.
Chapter 6: Culture Kinetic Study of Modifying Continuous Fermentation
- Chemostat with Cell Recycle
- Multistage Chemostat System
Please do the exercise.
Chapter 7: Stoichiometry of Microbial Growth and Product Formation
- Introduction
- Stoichiometric Calculation using Elemental Balances
Please do the exercise.
Chapter 8: Bioreactor/Fermenter Systems
- Introduction
- Types of Bioreactor/Fermenter
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Chapter 9: Sterilization in Fermentation
- Introduction
- Medium Sterilization
- Air Sterilization
- Fermenter Sterilization
Please do the exercise.
Chapter 10: Scale-up of Bioreactor
- Introduction
- Criteria of Scale-up
- Scale-down
Please do the exercise.